Goiter, an enlargement of the thyroid gland, producing a large lump on one side of the throat. The cause is not understood, but it is supposed to be in some way associated with the quality of drinking water. It is prevalent about the eastern end of Lake Ontario; in some parts of Michigan; in the cantons of Freiburg and Berne, Switzerland; in the southern Alps, and in Savoy; in England, where it is called Derbyshire neck; in far Siberia, and in the heights of the Himalayas. In some sections of Europe eighty per cent of the inhabitants are afflicted with goiter. Physicians recommend bathing the goiter with tincture of iodine, and a change of residence. Exposure to the rays of the sun seems to have a beneficial effect. It is more common in women than in men, and is most likely to appear in middle age.